ENROFLOXACIN (Bovine, porcine, poultry)
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چکیده
1. Enrofloxacin (CAS: 93106-60-6) is a synthetic fluoroquinolone antimicrobial agent. In veterinary medicine it is administered by subcutaneous injection to cattle and intramuscular injection to pigs and orally to cattle, pigs, turkeys and chickens, for the treatment of infections of the respiratory and alimentary tract. The recommended doses are 2.5 to 5 mg enrofloxacin/kg bw/day for 3 to 5 days (cattle and pigs) or 10 mg enrofloxacin/kg bw/day for 3 to 10 days (chickens and turkeys). In some Member States, enrofloxacin is authorised for use in sheep, goats and rabbits; the dosage regime was not provided for these species. Ciprofloxacin, a major metabolite of enrofloxacin, is widely used in human medicine.
منابع مشابه
Fluoroquinolones Resistance of Campylobacter Jejuni and Campylobacter Coli Isolated from Poultry in 1994-1996 and 2005-2008 in Poland
The aim of the research was the determination of resistance to fluoroquinolones (ciprofloxacin and enrofloxacin) of 387 Campylobacter sp. strains isolated from poultry between 1994-1996 (broilers, laying hens) and between 2005-2008 (broilers, laying hens, and turkeys). The resistance was determined by an agar dilution method (MIC), with accordance to Clinical and Laboratory Standards Institute ...
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The interaction between enrofloxacin and porcine phagocytes was studied with clinically relevant concentrations of enrofloxacin. Enrofloxacin accumulated in phagocytes, with cellular concentration/extracellular concentration ratios of 9 for polymorphonuclear leukocytes (PMNs) and 5 for alveolar macrophages (AMs). Cells with accumulated enrofloxacin brought into enrofloxacin-free medium released...
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